Volume 2: Creatine MOA

Adapted from: 

Forbes, S.C.; Candow, D.G.; Smith-Ryan, A.E.; Hirsch, K.R.; Roberts, M.D.; VanDusseldorp, T.A.; Stratton, M.T.; Kaviani, M.; Little, J.P. Supplements and Nutritional Interventions to Augment High-Intensity Interval Training Physiological and Performance Adaptations—A Narrative Review. Nutrients 202012, 390. Click here to read the full study

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14. Terjung, R.L.; Clarkson, P.; Eichner, E.R.; Greenhaff, P.L.; Hespel, P.J.; Israel, R.G.; Kraemer, W.J.; Meyer, R.A.; Spriet, L.L.; Tarnopolsky, M.A.; et al. American College of Sports Medicine roundtable. The physiological and health effects of oral creatine supplementation. Med. Sci. Sports Exerc. 200032, 706–717. [Google Scholar]

15. Kreider, R.B.; Kalman, D.S.; Antonio, J.; Ziegenfuss, T.N.; Wildman, R.; Collins, R.; Candow, D.G.; Kleiner, S.M.; Almada, A.L.; Lopez, H.L. International Society of Sports Nutrition position stand: Safety and efficacy of creatine supplementation in exercise, sport, and medicine. J. Int. Soc. Sports Nutr. 201714, 18-z, eCollection 2017. [Google Scholar] [CrossRef] [PubMed]

16. Wyss, M.; Kaddurah-Daouk, R. Creatine and creatinine metabolism. Physiol. Rev. 200080, 1107–1213. [Google Scholar] [CrossRef]

17. Deminice, R.; Jordao, A.A. Creatine supplementation reduces oxidative stress biomarkers after acute exercise in rats. Amino Acids 201243, 709–715. [Google Scholar] [CrossRef]

18. Deminice, R.; Rosa, F.T.; Franco, G.S.; Jordao, A.A.; de Freitas, E.C. Effects of creatine supplementation on oxidative stress and inflammatory markers after repeated-sprint exercise in humans. Nutrition 201329, 1127–1132. [Google Scholar] [CrossRef]

19. Cooper, R.; Naclerio, F.; Allgrove, J.; Jimenez, A. Creatine supplementation with specific view to exercise/sports performance: An update. J. Int. Soc. Sports Nutr. 20129, 33. [Google Scholar] [CrossRef]

20. Hespel, P.; Op’t Eijnde, B.; Van Leemputte, M. Opposite actions of caffeine and creatine on muscle relaxation time in humans. J. Appl. Physiol. (1985) 200292, 513–518. [Google Scholar] [CrossRef]